Slc11a2 Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comSlc11a2 Polyclonal Antibody for Rat(Rattus norvegicus)

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Index > Protein center > Slc11a2(Gene name) > Rat

Slc11a2 (Gene name),

Natural resistance-associated macrophage protein 2 (Protein name ), NRAM2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Slc11a2(Dct1;Dmt1;Nramp2);

Protein name:

Natural resistance-associated macrophage protein 2(NRAMP 2);

Alternative:

Divalent metal transporter 1(DMT-1);Divalent cation transporter 1;Solute carrier family 11 member 2;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Forms a complex with NDFIP1 and NEDD4L, in cortical neurons, in response to iron and colbalt exposure; this interaction leads to ubiquitination by NEDD4L and proteasome-dependent degradation. Interacts with NDFIP2.

Function:

Important in metal transport, in particular iron. Can also transport zinc, manganese, cobalt, cadmium, copper, nickel and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution.

Subcellular Location:

Endosome membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

568

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

568:

RPEIYLLNTV | DAVSLVSR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:25715

Pfam:

PF01566

STRING:

10116.ENSRNOP00000026494

String:

O54902

UniGene:

Rn.11418

Uniprot:

O54902

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ELISA Kit for Rat NRAMP 2

Cat.:

E0316r

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Packing:

96T

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ELISA Kit for Rat NRAMP 2

Cat.:

E0316h

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96T

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ELISA Kit for Rat NRAMP 2

Cat.:

E0316m

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MSDS:

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Packing:

96T

CLIA Kit for Rat NRAMP 2

Cat.:

U0316m

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Packing:

96T

CLIA Kit for Rat NRAMP 2

Cat.:

U0316h

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96T

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CLIA Kit for Rat NRAMP 2

Cat.:

U0316r

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96T

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Polyclonal Antibody for Rat NRAMP 2

Cat.:

P0316Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat NRAMP 2

Cat.:

P0316Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat NRAMP 2

Cat.:

P0316Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat NRAMP 2

Protein for Rat NRAMP 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and characterization of a mammalian proton-coupled metal-ion transporter."
Gunshin H. , Mackenzie B. , Berger U.V. , Gunshin Y. , Romero M.F. , Boron W.F. , Nussberger S. , Gollan J.L. , Hediger M.A.
Nature388:482-488(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION
strain: Sprague-Dawley.
2.

"Rat natural resistance associated macrophage protein-2 (Nramp2), C-terminal exon alternative splice variant."
Fleming M.D. , Romano M.A. , Su M.A. , Garrick L.M. , Garrick M.D. , Andrews N.C.
Submitted (1997-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Cerebellum.
3.

"Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport."
Fleming M.D. , Romano M.A. , Su M.A. , Garrick L.M. , Garrick M.D. , Andrews N.C.
Proc. Natl. Acad. Sci. U.S.A.95:1148-1153(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT B ARG-185

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